Human Growth Hormone is a hormone produced by the anterior pituitary gland in the brain. Human Growth Hormone promotes

• Tissue repair
• Cell regeneration in the bones
• muscles and vital organs
• supports the immune system in combating infection and disease.

As the body's cells die off, HGH acts as a “trigger” to ensure that replacement cells are healthy and readily available. The eight hormones produced or stored by the pituitary gland are responsible for many symptoms of aging. Several such hormones reach their peak in puberty and then decline. The exact reason why the pituitary gland’s production falls so rapidly remains a mystery. By the age of forty nearly everyone is deficient in HGH, and at eighty the body’s production has usually diminished by 90-95%. Many of the diseases and symptoms associated with aging can be traced to declining levels of HGH being produced by the body.

When studying Human Growth Hormone, it is very important and critical to understand that there are two main effects:

·         Direct effects are the result of growth hormone binding its receptor on target cells. Fat cells (adipocytes), for example, have growth hormone receptors, and growth hormone stimulates them to break down triglyceride and suppresses their ability to take up and accumulate circulating lipids.

• Indirect effects are mediated primarily by a insulin-like growth factor-1 (IGF-1), a hormone that is secreted from the liver and other tissues in response to growth hormone. A majority of the growth promoting effects of growth hormone is actually due to IGF-1 acting on its target cells.

Two major roles of HGH and IGF-1 are the effects on Growth and Metabolism which generates the amazing results so quickly is especially the older generation where such hormones are not so readily produced. 

Growth Effects:  Growth hormone is responsible for stimulating the liver and other tissues to secrete IGF-1, which in turn, stimulates proliferation of chondrocytes and myoblasts, resulting in bone growth and and muscle growth.

Metabolic Effects:  HGH seems to indirectly effect protein, lipid and carbohydrate metabolism via IGF-1 playing the critical mediator.  HGH stimulates protein anabolism, triglyceride breakdown and serves to maintain a balanced blood glucose and insulin levels.

 

  Your body’s natural HGH is a complex hormone composed of 191 amino acids. The first true synthetic human growth hormone, (called Somatotropin) was first produced in 1986 by the Eli Lily Corporation.  It was used in and injected HGH form.  In 1990 a ground-breaking (and oft-cited) study was published by Dr Rudman in the New England Journal of Medicine.  While this was a truly amazing discovery under strict scientific scrutiny, the high cost, pain, and risk of injections prevented Human Growth Hormone from becoming widely accepted in the United States. Attempts to produce an oral form of Somatotropin did not work; it was incredibly costly to produce, the liver broke down Somatotropin ingested into the stomach, and the HGH molecule was too large to be absorbed through the lining of the mouth.

True synthetic injectable hormone remains available today by prescription, but its price ($1000-1500 per daily injection) puts it well outside the pocketbooks of most people. The HGH supplements more commonly available today without a prescription fall into one of two categories, releasers and secretagogues.

Releasers are the least expensive HGH products available today. Releasers provide the building blocks of the 191 amino acid human growth hormone, predominately L-group amino acids such as L-valine and L-arginine. While these are components of true HGH, they are several chemical conversion steps away from actually being HGH. Just as a pile of wood and nails is not the same as house, releasers are not the same as true human growth hormone.

Secretagogues

The other main HGH supplements are secretagogues. Secretagogues contain minute amounts of human growth hormone substance (usually measured in nanograms, or hundredths of a gram). Secretagogues are a form of homeopathic medicine. Homeopathic medicine promotes the use of tiny amounts of a natural body chemical taken to stimulate the body to produce more. Absorbing small amounts of a synthetic hormone can cause the pituitary gland to secrete more of its own natural human growth hormone into the bloodstream. Secretagogues can contain actual human growth hormone and still be available without a prescription, but only if they do so in very small amounts. Any supplement that claims to have any significant amount of true human growth hormone and is available without a prescription is either misleading you about the true nature of their product, or is in direct violation of federal law.